Rum-filled pirates polluting the high seas is probably not in anyone's best interest, particularly the Far Seas Trading Company, so I'd better disrupt the Brokenskulls' rum operation. To make a thorough job of it, I'll want to do the following, in no particular order:

1: Add something disgusting to the copper stills to spoil their distillation
2: Jam the water pump to prevent any further fermentation
3: Kill their last sugar cane press mechanic (that old machine won't last a day without proper maintenance)
4: Burn the rum master's rum recipes